Difference between revisions of "YPR033C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006237 YPR033C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HTS1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HTS1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:639019..637379 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000006237 | ||
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| − | '''Description of | + | '''Description of YPR033C:''' Cytoplasmic and mitochondrial histidine tRNA synthetase; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence; mutations in human ortholog HARS2 are associated with Perrault syndrome<ref name='S000042552'>Chiu MI, et al. (1992) HTS1 encodes both the cytoplasmic and mitochondrial histidyl-tRNA synthetase of Saccharomyces cerevisiae: mutations alter the specificity of compartmentation. Genetics 132(4):987-1001 {{SGDpaper|S000042552}} PMID 1459448</ref><ref name='S000043557'>Natsoulis G, et al. (1986) The HTS1 gene encodes both the cytoplasmic and mitochondrial histidine tRNA synthetases of S. cerevisiae. Cell 46(2):235-43 {{SGDpaper|S000043557}} PMID 3521891</ref><ref name='S000144967'>Pierce SB, et al. (2011) Mutations in mitochondrial histidyl tRNA synthetase HARS2 cause ovarian dysgenesis and sensorineural hearing loss of Perrault syndrome. Proc Natl Acad Sci U S A 108(16):6543-8 |
| − | {{SGDpaper| | + | {{SGDpaper|S000144967}} PMID 21464306</ref> |
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YPR033C |
| Gene name | HTS1 |
| Aliases | TSM4572 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:639019..637379 |
| Primary SGDID | S000006237 |
Description of YPR033C: Cytoplasmic and mitochondrial histidine tRNA synthetase; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence; mutations in human ortholog HARS2 are associated with Perrault syndrome[1][2][3]
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References
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- ↑ Chiu MI, et al. (1992) HTS1 encodes both the cytoplasmic and mitochondrial histidyl-tRNA synthetase of Saccharomyces cerevisiae: mutations alter the specificity of compartmentation. Genetics 132(4):987-1001 SGD PMID 1459448
- ↑ Natsoulis G, et al. (1986) The HTS1 gene encodes both the cytoplasmic and mitochondrial histidine tRNA synthetases of S. cerevisiae. Cell 46(2):235-43 SGD PMID 3521891
- ↑ Pierce SB, et al. (2011) Mutations in mitochondrial histidyl tRNA synthetase HARS2 cause ovarian dysgenesis and sensorineural hearing loss of Perrault syndrome. Proc Natl Acad Sci U S A 108(16):6543-8 SGD PMID 21464306
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