YPL268W
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| Systematic name | YPL268W |
| Gene name | PLC1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:35236..37845 |
Description of YPL268W: Phosphoinositide-specific phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in kinetochore function and pseudohyphal differentiation[1][2][3][4]
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References
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- ↑ York JD, et al. (1999) A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. Science 285(5424):96-100 SGD PMID 10390371
- ↑ Lin H, et al. (2000) Phospholipase C is involved in kinetochore function in Saccharomyces cerevisiae. Mol Cell Biol 20(10):3597-607 SGD PMID 10779349
- ↑ Yoko-o T, et al. (1995) Isolation and characterization of temperature-sensitive plc1 mutants of the yeast Saccharomyces cerevisiae. Mol Gen Genet 247(2):148-56 SGD PMID 7753023
- ↑ Flick JS and Thorner J (1998) An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae. Genetics 148(1):33-47 SGD PMID 9475719
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