YPL268W

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Systematic name YPL268W
Gene name PLC1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:35236..37845
Primary SGDID S000006189


Description of YPL268W: Phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes[1][2]




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References

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  1. Flick JS and Thorner J (1998) An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae. Genetics 148(1):33-47 SGD PMID 9475719
  2. Yoko-o T, et al. (1995) Isolation and characterization of temperature-sensitive plc1 mutants of the yeast Saccharomyces cerevisiae. Mol Gen Genet 247(2):148-56 SGD PMID 7753023

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