Difference between revisions of "YPL268W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YPL268W
Gene name PLC1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:35236..37845


Description of YPL268W: Phosphoinositide-specific phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in kinetochore function and pseudohyphal differentiation[1][2][3][4]




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References

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  1. York JD, et al. (1999) A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. Science 285(5424):96-100 SGD PMID 10390371
  2. Lin H, et al. (2000) Phospholipase C is involved in kinetochore function in Saccharomyces cerevisiae. Mol Cell Biol 20(10):3597-607 SGD PMID 10779349
  3. Yoko-o T, et al. (1995) Isolation and characterization of temperature-sensitive plc1 mutants of the yeast Saccharomyces cerevisiae. Mol Gen Genet 247(2):148-56 SGD PMID 7753023
  4. Flick JS and Thorner J (1998) An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae. Genetics 148(1):33-47 SGD PMID 9475719

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