Difference between revisions of "YOR274W"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
| (2 intermediate revisions by the same user not shown) | |||
| Line 4: | Line 4: | ||
{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
|- | |- | ||
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005800 YOR274W] |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MOD5 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MOD5 '' | ||
| Line 13: | Line 13: | ||
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XV: | + | |nowrap| Chr XV:837674..838960 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005800 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005800 | ||
|} | |} | ||
<br> | <br> | ||
| − | '''Description of YOR274W:''' Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase | + | '''Description of YOR274W:''' Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase; required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; gene is nuclear and encodes two isozymic forms; converts to a prion form, and prion conversion contributes to azole antifungal resistance by upregulating ergosterol biosynthesis<ref name='S000051677'>Dihanich ME, et al. (1987) Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae. Mol Cell Biol 7(1):177-84 {{SGDpaper|S000051677}} PMID 3031456</ref><ref name='S000051678'>Najarian D, et al. (1987) DNA sequence and transcript mapping of MOD5: features of the 5' region which suggest two translational starts. Mol Cell Biol 7(1):185-91 {{SGDpaper|S000051678}} PMID 3031457</ref><ref name='S000044319'>Slusher LB, et al. (1991) mRNA leader length and initiation codon context determine alternative AUG selection for the yeast gene MOD5. Proc Natl Acad Sci U S A 88(21):9789-93 {{SGDpaper|S000044319}} PMID 1946403</ref><ref name='S000149323'>Suzuki G, et al. (2012) A yeast prion, Mod5, promotes acquired drug resistance and cell survival under environmental stress. Science 336(6079):355-9 |
| − | {{SGDpaper| | + | {{SGDpaper|S000149323}} PMID 22517861</ref> |
<br> | <br> | ||
<br> | <br> | ||
Latest revision as of 14:05, 21 June 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YOR274W |
| Gene name | MOD5 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:837674..838960 |
| Primary SGDID | S000005800 |
Description of YOR274W: Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase; required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; gene is nuclear and encodes two isozymic forms; converts to a prion form, and prion conversion contributes to azole antifungal resistance by upregulating ergosterol biosynthesis[1][2][3][4]
</protect>
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
<protect>
References
See Help:References on how to add references
- ↑ Dihanich ME, et al. (1987) Isolation and characterization of MOD5, a gene required for isopentenylation of cytoplasmic and mitochondrial tRNAs of Saccharomyces cerevisiae. Mol Cell Biol 7(1):177-84 SGD PMID 3031456
- ↑ Najarian D, et al. (1987) DNA sequence and transcript mapping of MOD5: features of the 5' region which suggest two translational starts. Mol Cell Biol 7(1):185-91 SGD PMID 3031457
- ↑ Slusher LB, et al. (1991) mRNA leader length and initiation codon context determine alternative AUG selection for the yeast gene MOD5. Proc Natl Acad Sci U S A 88(21):9789-93 SGD PMID 1946403
- ↑ Suzuki G, et al. (2012) A yeast prion, Mod5, promotes acquired drug resistance and cell survival under environmental stress. Science 336(6079):355-9 SGD PMID 22517861
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
