Difference between revisions of "YOL147C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YOL147C YOL147C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005507 YOL147C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PEX11 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PEX11 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XV:48642..47932
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|nowrap| Chr XV:48643..47933
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005507
 
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'''Description of {{PAGENAME}}:''' Peroxisomal membrane protein required for peroxisome proliferation and medium-chain fatty acid oxidation, most abundant protein in the peroxisomal membrane, regulated by Adr1p and Pip2p-Oaf1p, promoter contains ORE and UAS1-like elements<ref name='S000061271'>Gurvitz A, et al. (2001) Saccharomyces cerevisiae Adr1p governs fatty acid beta-oxidation and peroxisome proliferation by regulating POX1 and PEX11. J Biol Chem 276(34):31825-30 {{SGDpaper|S000061271}} PMID 11431484</ref><ref name='S000052800'>van Roermund CW, et al. (2000) Pex11p plays a primary role in medium-chain fatty acid oxidation, a process that affects peroxisome number and size in Saccharomyces cerevisiae. J Cell Biol 150(3):489-98 {{SGDpaper|S000052800}} PMID 10931862</ref><ref name='S000051331'>Erdmann R and Blobel G (1995) Giant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p. J Cell Biol 128(4):509-23
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'''Description of YOL147C:''' Peroxisomal membrane protein required for medium-chain fatty acid oxidation and peroxisome proliferation, possibly by inducing membrane curvature; localization regulated by phosphorylation; transcription regulated by Adr1p and Pip2p-Oaf1p<ref name='S000051331'>Erdmann R and Blobel G (1995) Giant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p. J Cell Biol 128(4):509-23 {{SGDpaper|S000051331}} PMID 7860627</ref><ref name='S000061271'>Gurvitz A, et al. (2001) Saccharomyces cerevisiae Adr1p governs fatty acid beta-oxidation and peroxisome proliferation by regulating POX1 and PEX11. J Biol Chem 276(34):31825-30 {{SGDpaper|S000061271}} PMID 11431484</ref><ref name='S000132564'>Knoblach B and Rachubinski RA (2010) Phosphorylation-dependent Activation of Peroxisome Proliferator Protein PEX11 Controls Peroxisome Abundance. J Biol Chem 285(9):6670-80 {{SGDpaper|S000132564}} PMID 20028986</ref><ref name='S000141497'>Opalinski L, et al. (2011) Membrane curvature during peroxisome fission requires Pex11. EMBO J 30(1):5-16 {{SGDpaper|S000141497}} PMID 21113128</ref><ref name='S000052800'>van Roermund CW, et al. (2000) Pex11p plays a primary role in medium-chain fatty acid oxidation, a process that affects peroxisome number and size in Saccharomyces cerevisiae. J Cell Biol 150(3):489-98
{{SGDpaper|S000051331}} PMID 7860627</ref>
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{{SGDpaper|S000052800}} PMID 10931862</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 07:45, 23 January 2012

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Systematic name YOL147C
Gene name PEX11
Aliases PMP24, PMP27
Feature type ORF, Verified
Coordinates Chr XV:48643..47933
Primary SGDID S000005507


Description of YOL147C: Peroxisomal membrane protein required for medium-chain fatty acid oxidation and peroxisome proliferation, possibly by inducing membrane curvature; localization regulated by phosphorylation; transcription regulated by Adr1p and Pip2p-Oaf1p[1][2][3][4][5]




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Community Commentary

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References

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  1. Erdmann R and Blobel G (1995) Giant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p. J Cell Biol 128(4):509-23 SGD PMID 7860627
  2. Gurvitz A, et al. (2001) Saccharomyces cerevisiae Adr1p governs fatty acid beta-oxidation and peroxisome proliferation by regulating POX1 and PEX11. J Biol Chem 276(34):31825-30 SGD PMID 11431484
  3. Knoblach B and Rachubinski RA (2010) Phosphorylation-dependent Activation of Peroxisome Proliferator Protein PEX11 Controls Peroxisome Abundance. J Biol Chem 285(9):6670-80 SGD PMID 20028986
  4. Opalinski L, et al. (2011) Membrane curvature during peroxisome fission requires Pex11. EMBO J 30(1):5-16 SGD PMID 21113128
  5. van Roermund CW, et al. (2000) Pex11p plays a primary role in medium-chain fatty acid oxidation, a process that affects peroxisome number and size in Saccharomyces cerevisiae. J Cell Biol 150(3):489-98 SGD PMID 10931862

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