YOL147C

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Systematic name YOL147C
Gene name PEX11
Aliases PMP24, PMP27
Feature type ORF, Verified
Coordinates Chr XV:48643..47933
Primary SGDID S000005507


Description of YOL147C: Peroxisomal membrane protein required for medium-chain fatty acid oxidation and peroxisome proliferation, possibly by inducing membrane curvature; localization regulated by phosphorylation; transcription regulated by Adr1p and Pip2p-Oaf1p[1][2][3][4][5]




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References

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  1. Erdmann R and Blobel G (1995) Giant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p. J Cell Biol 128(4):509-23 SGD PMID 7860627
  2. Gurvitz A, et al. (2001) Saccharomyces cerevisiae Adr1p governs fatty acid beta-oxidation and peroxisome proliferation by regulating POX1 and PEX11. J Biol Chem 276(34):31825-30 SGD PMID 11431484
  3. Knoblach B and Rachubinski RA (2010) Phosphorylation-dependent Activation of Peroxisome Proliferator Protein PEX11 Controls Peroxisome Abundance. J Biol Chem 285(9):6670-80 SGD PMID 20028986
  4. Opalinski L, et al. (2011) Membrane curvature during peroxisome fission requires Pex11. EMBO J 30(1):5-16 SGD PMID 21113128
  5. van Roermund CW, et al. (2000) Pex11p plays a primary role in medium-chain fatty acid oxidation, a process that affects peroxisome number and size in Saccharomyces cerevisiae. J Cell Biol 150(3):489-98 SGD PMID 10931862

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