Difference between revisions of "YNL241C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005185 YNL241C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ZWF1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ZWF1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XIV:197944..196427 | |nowrap| Chr XIV:197944..196427 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005185 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YNL241C:''' Glucose-6-phosphate dehydrogenase (G6PD), catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidatve stress; homolog of the human G6PD which is deficient in patients with hemolytic anemia<ref name='S000082209'>Blank LM, et al. (2005) Large-scale 13C-flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeast. Genome Biol 6(6):R49 {{SGDpaper|S000082209}} PMID 15960801</ref><ref name='S000074623'>Grabowska D, et al. (2004) A novel mutation in the glucose-6-phosphate dehydrogenase gene in a subject with chronic nonspherocytic hemolytic anemia--characterization of enzyme using yeast expression system and molecular modeling. Blood Cells Mol Dis 32(1):124-30 {{SGDpaper|S000074623}} PMID 14757426</ref><ref name='S000061566'>Izawa S, et al. (1998) Importance of glucose-6-phosphate dehydrogenase in the adaptive response to hydrogen peroxide in Saccharomyces cerevisiae. Biochem J 330 ( Pt 2)():811-7 {{SGDpaper|S000061566}} PMID 9480895</ref><ref name='S000043047'>Nogae I and Johnston M (1990) Isolation and characterization of the ZWF1 gene of Saccharomyces cerevisiae, encoding glucose-6-phosphate dehydrogenase. Gene 96(2):161-9 |
{{SGDpaper|S000043047}} PMID 2269430</ref> | {{SGDpaper|S000043047}} PMID 2269430</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YNL241C |
| Gene name | ZWF1 |
| Aliases | MET19, POS10 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:197944..196427 |
| Primary SGDID | S000005185 |
Description of YNL241C: Glucose-6-phosphate dehydrogenase (G6PD), catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidatve stress; homolog of the human G6PD which is deficient in patients with hemolytic anemia[1][2][3][4]
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References
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- ↑ Blank LM, et al. (2005) Large-scale 13C-flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeast. Genome Biol 6(6):R49 SGD PMID 15960801
- ↑ Grabowska D, et al. (2004) A novel mutation in the glucose-6-phosphate dehydrogenase gene in a subject with chronic nonspherocytic hemolytic anemia--characterization of enzyme using yeast expression system and molecular modeling. Blood Cells Mol Dis 32(1):124-30 SGD PMID 14757426
- ↑ Izawa S, et al. (1998) Importance of glucose-6-phosphate dehydrogenase in the adaptive response to hydrogen peroxide in Saccharomyces cerevisiae. Biochem J 330 ( Pt 2)():811-7 SGD PMID 9480895
- ↑ Nogae I and Johnston M (1990) Isolation and characterization of the ZWF1 gene of Saccharomyces cerevisiae, encoding glucose-6-phosphate dehydrogenase. Gene 96(2):161-9 SGD PMID 2269430
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