Difference between revisions of "YNL197C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YNL197C YNL197C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005141 YNL197C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''WHI3 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''WHI3 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIV:269594..267609
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|nowrap| Chr XIV:269593..267608
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005141
 
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'''Description of {{PAGENAME}}:''' RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start<ref name='S000076346'>Wang H, et al. (2004) Recruitment of Cdc28 by Whi3 restricts nuclear accumulation of the G1 cyclin-Cdk complex to late G1. EMBO J 23(1):180-90 {{SGDpaper|S000076346}} PMID 14685274</ref><ref name='S000073973'>Gari E, et al. (2001) Whi3 binds the mRNA of the G1 cyclin CLN3 to modulate cell fate in budding yeast. Genes Dev 15(21):2803-8 {{SGDpaper|S000073973}} PMID 11691832</ref><ref name='S000060206'>Nash RS, et al. (2001) Isolation and characterization of WHI3, a size-control gene of Saccharomyces cerevisiae. Genetics 157(4):1469-80 {{SGDpaper|S000060206}} PMID 11290704</ref><ref name='S000042772'>Mosch HU and Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671-84
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'''Description of YNL197C:''' RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start<ref name='S000073973'>Gari E, et al. (2001) Whi3 binds the mRNA of the G1 cyclin CLN3 to modulate cell fate in budding yeast. Genes Dev 15(21):2803-8 {{SGDpaper|S000073973}} PMID 11691832</ref><ref name='S000042772'>Mosch HU and Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671-84 {{SGDpaper|S000042772}} PMID 9055077</ref><ref name='S000060206'>Nash RS, et al. (2001) Isolation and characterization of WHI3, a size-control gene of Saccharomyces cerevisiae. Genetics 157(4):1469-80 {{SGDpaper|S000060206}} PMID 11290704</ref><ref name='S000076346'>Wang H, et al. (2004) Recruitment of Cdc28 by Whi3 restricts nuclear accumulation of the G1 cyclin-Cdk complex to late G1. EMBO J 23(1):180-90
  {{SGDpaper|S000042772}} PMID 9055077</ref>
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  {{SGDpaper|S000076346}} PMID 14685274</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YNL197C
Gene name WHI3
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:269593..267608
Primary SGDID S000005141


Description of YNL197C: RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start[1][2][3][4]




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References

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  1. Gari E, et al. (2001) Whi3 binds the mRNA of the G1 cyclin CLN3 to modulate cell fate in budding yeast. Genes Dev 15(21):2803-8 SGD PMID 11691832
  2. Mosch HU and Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671-84 SGD PMID 9055077
  3. Nash RS, et al. (2001) Isolation and characterization of WHI3, a size-control gene of Saccharomyces cerevisiae. Genetics 157(4):1469-80 SGD PMID 11290704
  4. Wang H, et al. (2004) Recruitment of Cdc28 by Whi3 restricts nuclear accumulation of the G1 cyclin-Cdk complex to late G1. EMBO J 23(1):180-90 SGD PMID 14685274

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