YNL197C

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Systematic name YNL197C
Gene name WHI3
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:269593..267608
Primary SGDID S000005141


Description of YNL197C: RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start[1][2][3][4]




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References

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  1. Gari E, et al. (2001) Whi3 binds the mRNA of the G1 cyclin CLN3 to modulate cell fate in budding yeast. Genes Dev 15(21):2803-8 SGD PMID 11691832
  2. Mosch HU and Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671-84 SGD PMID 9055077
  3. Nash RS, et al. (2001) Isolation and characterization of WHI3, a size-control gene of Saccharomyces cerevisiae. Genetics 157(4):1469-80 SGD PMID 11290704
  4. Wang H, et al. (2004) Recruitment of Cdc28 by Whi3 restricts nuclear accumulation of the G1 cyclin-Cdk complex to late G1. EMBO J 23(1):180-90 SGD PMID 14685274

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