Difference between revisions of "YNL197C"

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'''Description of YNL197C:''' RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start<ref name='S000076346'>Wang H, et al. (2004) Recruitment of Cdc28 by Whi3 restricts nuclear accumulation of the G1 cyclin-Cdk complex to late G1. EMBO J 23(1):180-90 {{SGDpaper|S000076346}} PMID 14685274</ref><ref name='S000073973'>Gari E, et al. (2001) Whi3 binds the mRNA of the G1 cyclin CLN3 to modulate cell fate in budding yeast. Genes Dev 15(21):2803-8 {{SGDpaper|S000073973}} PMID 11691832</ref><ref name='S000060206'>Nash RS, et al. (2001) Isolation and characterization of WHI3, a size-control gene of Saccharomyces cerevisiae. Genetics 157(4):1469-80 {{SGDpaper|S000060206}} PMID 11290704</ref><ref name='S000042772'>Mosch HU and Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671-84
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'''Description of YNL197C:''' RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start<ref name='S000042772'>Mosch HU and Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671-84 {{SGDpaper|S000042772}} PMID 9055077</ref><ref name='S000060206'>Nash RS, et al. (2001) Isolation and characterization of WHI3, a size-control gene of Saccharomyces cerevisiae. Genetics 157(4):1469-80 {{SGDpaper|S000060206}} PMID 11290704</ref><ref name='S000076346'>Wang H, et al. (2004) Recruitment of Cdc28 by Whi3 restricts nuclear accumulation of the G1 cyclin-Cdk complex to late G1. EMBO J 23(1):180-90 {{SGDpaper|S000076346}} PMID 14685274</ref><ref name='S000073973'>Gari E, et al. (2001) Whi3 binds the mRNA of the G1 cyclin CLN3 to modulate cell fate in budding yeast. Genes Dev 15(21):2803-8
  {{SGDpaper|S000042772}} PMID 9055077</ref>
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  {{SGDpaper|S000073973}} PMID 11691832</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YNL197C
Gene name WHI3
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:269594..267609
Primary SGDID S000005141


Description of YNL197C: RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start[1][2][3][4]




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References

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  1. Mosch HU and Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671-84 SGD PMID 9055077
  2. Nash RS, et al. (2001) Isolation and characterization of WHI3, a size-control gene of Saccharomyces cerevisiae. Genetics 157(4):1469-80 SGD PMID 11290704
  3. Wang H, et al. (2004) Recruitment of Cdc28 by Whi3 restricts nuclear accumulation of the G1 cyclin-Cdk complex to late G1. EMBO J 23(1):180-90 SGD PMID 14685274
  4. Gari E, et al. (2001) Whi3 binds the mRNA of the G1 cyclin CLN3 to modulate cell fate in budding yeast. Genes Dev 15(21):2803-8 SGD PMID 11691832

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