Difference between revisions of "YMR228W"
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| − | '''Description of YMR228W:''' Mitochondrial RNA polymerase specificity factor | + | '''Description of YMR228W:''' Mitochondrial RNA polymerase specificity factor; has structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors; binding of Mtf1p to the core polymerase (Rpo41p)-promoter complex stabilizes the binding and induces DNA bending<ref name='S000039346'>Mangus DA, et al. (1994) Release of the yeast mitochondrial RNA polymerase specificity factor from transcription complexes. J Biol Chem 269(42):26568-74 {{SGDpaper|S000039346}} PMID 7929382</ref><ref name='S000079841'>Matsunaga M and Jaehning JA (2004) Intrinsic promoter recognition by a core RNA polymerase. J Biol Chem 279(43):44239-42 {{SGDpaper|S000079841}} PMID 15342628</ref><ref name='S000067659'>Schubot FD, et al. (2001) Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription. Protein Sci 10(10):1980-8 {{SGDpaper|S000067659}} PMID 11567089</ref><ref name='S000146745'>Tang GQ, et al. (2011) Transcription factor-dependent DNA bending governs promoter recognition by the mitochondrial RNA polymerase. J Biol Chem () |
| − | {{SGDpaper| | + | {{SGDpaper|S000146745}} PMID 21911502</ref> |
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Revision as of 14:05, 5 October 2011
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| Systematic name | YMR228W |
| Gene name | MTF1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:724626..725651 |
| Primary SGDID | S000004841 |
Description of YMR228W: Mitochondrial RNA polymerase specificity factor; has structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors; binding of Mtf1p to the core polymerase (Rpo41p)-promoter complex stabilizes the binding and induces DNA bending[1][2][3][4]
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References
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- ↑ Mangus DA, et al. (1994) Release of the yeast mitochondrial RNA polymerase specificity factor from transcription complexes. J Biol Chem 269(42):26568-74 SGD PMID 7929382
- ↑ Matsunaga M and Jaehning JA (2004) Intrinsic promoter recognition by a core RNA polymerase. J Biol Chem 279(43):44239-42 SGD PMID 15342628
- ↑ Schubot FD, et al. (2001) Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription. Protein Sci 10(10):1980-8 SGD PMID 11567089
- ↑ Tang GQ, et al. (2011) Transcription factor-dependent DNA bending governs promoter recognition by the mitochondrial RNA polymerase. J Biol Chem () SGD PMID 21911502
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