Difference between revisions of "YMR020W"
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| − | '''Description of YMR020W:''' Polyamine oxidase, converts spermine to spermidine, which is required for the essential hypusination modification of translation factor eIF-5A; also involved in pantothenic acid biosynthesis<ref name=' | + | '''Description of YMR020W:''' Polyamine oxidase, converts spermine to spermidine, which is required for the essential hypusination modification of translation factor eIF-5A; also involved in pantothenic acid biosynthesis<ref name='S000060103'>White WH, et al. (2001) Saccharomyces cerevisiae is capable of de Novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine. J Biol Chem 276(14):10794-800 {{SGDpaper|S000060103}} PMID 11154694</ref><ref name='S000072966'>Landry J and Sternglanz R (2003) Yeast Fms1 is a FAD-utilizing polyamine oxidase. Biochem Biophys Res Commun 303(3):771-6 {{SGDpaper|S000072966}} PMID 12670477</ref><ref name='S000074740'>Chattopadhyay MK, et al. (2003) Spermidine but not spermine is essential for hypusine biosynthesis and growth in Saccharomyces cerevisiae: spermine is converted to spermidine in vivo by the FMS1-amine oxidase. Proc Natl Acad Sci U S A 100(24):13869-74 |
| − | {{SGDpaper| | + | {{SGDpaper|S000074740}} PMID 14617780</ref> |
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Revision as of 14:05, 31 March 2009
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| Systematic name | YMR020W |
| Gene name | FMS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:315376..316902 |
| Primary SGDID | S000004622 |
Description of YMR020W: Polyamine oxidase, converts spermine to spermidine, which is required for the essential hypusination modification of translation factor eIF-5A; also involved in pantothenic acid biosynthesis[1][2][3]
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References
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- ↑ White WH, et al. (2001) Saccharomyces cerevisiae is capable of de Novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine. J Biol Chem 276(14):10794-800 SGD PMID 11154694
- ↑ Landry J and Sternglanz R (2003) Yeast Fms1 is a FAD-utilizing polyamine oxidase. Biochem Biophys Res Commun 303(3):771-6 SGD PMID 12670477
- ↑ Chattopadhyay MK, et al. (2003) Spermidine but not spermine is essential for hypusine biosynthesis and growth in Saccharomyces cerevisiae: spermine is converted to spermidine in vivo by the FMS1-amine oxidase. Proc Natl Acad Sci U S A 100(24):13869-74 SGD PMID 14617780
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