Difference between revisions of "YML013W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YML013W
Gene name SEL1
Aliases UBX2
Feature type ORF, Verified
Coordinates Chr XIII:244149..245903


Description of YML013W: Protein involved in ER-associated protein degradation; proposed to coordinate the assembly of proteins involved in ERAD; contains a UBX (ubiquitin regulatory X) domain and a ubiquitin-associated (UBA) domain[1][2][3]




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References

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  1. Schuberth C and Buchberger A (2005) Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation. Nat Cell Biol 7(10):999-1006 SGD PMID 16179952
  2. Schuberth C, et al. (2004) Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation. EMBO Rep 5(8):818-24 SGD PMID 15258615
  3. Bartkeviciute D and Sasnauskas K (2003) Studies of yeast Kluyveromyces lactis mutations conferring super-secretion of recombinant proteins. Yeast 20(1):1-11 SGD PMID 12489121

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