YLR223C
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| Systematic name | YLR223C |
| Gene name | IFH1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:585492..582235 |
| Primary SGDID | S000004213 |
Description of YLR223C: Essential protein with a highly acidic N-terminal domain; IFH1 exhibits genetic interactions with FHL1, overexpression interferes with silencing at telomeres and HM loci; potential Cdc28p substrate[1][2]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]
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References
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- ↑ Singer MS, et al. (1998) Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics 150(2):613-32 SGD PMID 9755194
- ↑ Cherel I and Thuriaux P (1995) The IFH1 gene product interacts with a fork head protein in Saccharomyces cerevisiae. Yeast 11(3):261-70 SGD PMID 7785326
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
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