YLR195C
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Systematic name | YLR195C | |
Gene name | NMT1 | |
Aliases | CDC72 | |
Feature type | ORF, Verified | |
Coordinates | Chr XII:543306..541939 | |
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Description of YLR195C: N-myristoyl transferase, catalyzes the cotranslational, covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction[1][2][3][4]
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References
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- ↑ Towler DA, et al. (1987) Amino-terminal processing of proteins by N-myristoylation. Substrate specificity of N-myristoyl transferase. J Biol Chem 262(3):1030-6 SGD PMID 3100524
- ↑ Duronio RJ, et al. (1989) Disruption of the yeast N-myristoyl transferase gene causes recessive lethality. Science 243(4892):796-800 SGD PMID 2644694
- ↑ Stone DE, et al. (1991) N-myristoylation is required for function of the pheromone-responsive G alpha protein of yeast: conditional activation of the pheromone response by a temperature-sensitive N-myristoyl transferase. Genes Dev 5(11):1969-81 SGD PMID 1936988
- ↑ Knoll LJ, et al. (1992) Analysis of the compartmentalization of myristoyl-CoA:protein N-myristoyltransferase in Saccharomyces cerevisiae. J Biol Chem 267(8):5366-73 SGD PMID 1544917
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