YLR195C

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Systematic name YLR195C
Gene name NMT1
Aliases CDC72
Feature type ORF, Verified
Coordinates Chr XII:543304..541937
Primary SGDID S000004185


Description of YLR195C: N-myristoyl transferase, catalyzes the cotranslational, covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction[1][2][3][4]




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References

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  1. Duronio RJ, et al. (1989) Disruption of the yeast N-myristoyl transferase gene causes recessive lethality. Science 243(4892):796-800 SGD PMID 2644694
  2. Knoll LJ, et al. (1992) Analysis of the compartmentalization of myristoyl-CoA:protein N-myristoyltransferase in Saccharomyces cerevisiae. J Biol Chem 267(8):5366-73 SGD PMID 1544917
  3. Stone DE, et al. (1991) N-myristoylation is required for function of the pheromone-responsive G alpha protein of yeast: conditional activation of the pheromone response by a temperature-sensitive N-myristoyl transferase. Genes Dev 5(11):1969-81 SGD PMID 1936988
  4. Towler DA, et al. (1987) Amino-terminal processing of proteins by N-myristoylation. Substrate specificity of N-myristoyl transferase. J Biol Chem 262(3):1030-6 SGD PMID 3100524

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