YLR106C

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Systematic name YLR106C
Gene name MDN1
Aliases REA1
Feature type ORF, Verified
Coordinates Chr XII:363739..349007
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Description of YLR106C: Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p), may mediate ATP-dependent remodeling of 60S subunits and subsequent export from nucleoplasm to cytoplasm[1][2]



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References

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  1. Nissan TA, et al. (2004) A pre-ribosome with a tadpole-like structure functions in ATP-dependent maturation of 60S subunits. Mol Cell 15(2):295-301 SGD PMID 15260980
  2. Garbarino J and Gibbons I (2002) Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein. BMC Genomics 3(1):18 SGD PMID 12102729

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