Difference between revisions of "YLR106C"
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| − | '''Description of YLR106C:''' Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p) | + | '''Description of YLR106C:''' Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p); acts in removal of ribosomal biogenesis factors at successive steps of pre-60S assembly and export from nucleus<ref name='S000134635'>Bassler J, et al. (2010) The AAA-ATPase Rea1 drives removal of biogenesis factors during multiple stages of 60S ribosome assembly. Mol Cell 38(5):712-21 {{SGDpaper|S000134635}} PMID 20542003</ref><ref name='S000070139'>Garbarino J and Gibbons I (2002) Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein. BMC Genomics 3(1):18 {{SGDpaper|S000070139}} PMID 12102729</ref><ref name='S000077057'>Nissan TA, et al. (2004) A pre-ribosome with a tadpole-like structure functions in ATP-dependent maturation of 60S subunits. Mol Cell 15(2):295-301 {{SGDpaper|S000077057}} PMID 15260980</ref><ref name='S000131643'>Ulbrich C, et al. (2009) Mechanochemical removal of ribosome biogenesis factors from nascent 60S ribosomal subunits. Cell 138(5):911-22 |
| − | {{SGDpaper| | + | {{SGDpaper|S000131643}} PMID 19737519</ref> |
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Revision as of 14:05, 22 July 2010
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| Systematic name | YLR106C |
| Gene name | MDN1 |
| Aliases | REA1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:363739..349007 |
| Primary SGDID | S000004096 |
Description of YLR106C: Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p); acts in removal of ribosomal biogenesis factors at successive steps of pre-60S assembly and export from nucleus[1][2][3][4]
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References
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- ↑ Bassler J, et al. (2010) The AAA-ATPase Rea1 drives removal of biogenesis factors during multiple stages of 60S ribosome assembly. Mol Cell 38(5):712-21 SGD PMID 20542003
- ↑ Garbarino J and Gibbons I (2002) Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein. BMC Genomics 3(1):18 SGD PMID 12102729
- ↑ Nissan TA, et al. (2004) A pre-ribosome with a tadpole-like structure functions in ATP-dependent maturation of 60S subunits. Mol Cell 15(2):295-301 SGD PMID 15260980
- ↑ Ulbrich C, et al. (2009) Mechanochemical removal of ribosome biogenesis factors from nascent 60S ribosomal subunits. Cell 138(5):911-22 SGD PMID 19737519
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