Difference between revisions of "YLL027W"
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 13:02, 21 February 2007
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| Systematic name | YLL027W |
| Gene name | ISA1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:87402..88154 |
Description of YLL027W: Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources[1][2]
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References
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- ↑ Muhlenhoff U, et al. (2002) Characterization of iron-sulfur protein assembly in isolated mitochondria. A requirement for ATP, NADH, and reduced iron. J Biol Chem 277(33):29810-6 SGD PMID 12065597
- ↑ Jensen LT and Culotta VC (2000) Role of Saccharomyces cerevisiae ISA1 and ISA2 in iron homeostasis. Mol Cell Biol 20(11):3918-27 SGD PMID 10805735
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