Difference between revisions of "YKR084C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001792 YKR084C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HBS1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HBS1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XI: | + | |nowrap| Chr XI:598890..597055 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000001792 | ||
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| − | '''Description of | + | '''Description of YKR084C:''' GTPase with similarity to translation release factors; together with binding partner Dom34p, facilitates ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled; genetically implicated in mRNA no-go decay<ref name='S000069709'>Carr-Schmid A, et al. (2002) Novel G-protein complex whose requirement is linked to the translational status of the cell. Mol Cell Biol 22(8):2564-74 {{SGDpaper|S000069709}} PMID 11909951</ref><ref name='S000114969'>Doma MK and Parker R (2006) Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation. Nature 440(7083):561-4 {{SGDpaper|S000114969}} PMID 16554824</ref><ref name='S000041887'>Nelson RJ, et al. (1992) The translation machinery and 70 kd heat shock protein cooperate in protein synthesis. Cell 71(1):97-105 {{SGDpaper|S000041887}} PMID 1394434</ref><ref name='S000130237'>Passos DO, et al. (2009) Analysis of Dom34 and its function in no-go decay. Mol Biol Cell 20(13):3025-32 {{SGDpaper|S000130237}} PMID 19420139</ref><ref name='S000140925'>Shoemaker CJ, et al. (2010) Dom34:Hbs1 promotes subunit dissociation and peptidyl-tRNA drop-off to initiate no-go decay. Science 330(6002):369-72 |
| − | {{SGDpaper| | + | {{SGDpaper|S000140925}} PMID 20947765</ref> |
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==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YKR084C |
| Gene name | HBS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:598890..597055 |
| Primary SGDID | S000001792 |
Description of YKR084C: GTPase with similarity to translation release factors; together with binding partner Dom34p, facilitates ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled; genetically implicated in mRNA no-go decay[1][2][3][4][5]
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Community Commentary
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References
See Help:References on how to add references
- ↑ Carr-Schmid A, et al. (2002) Novel G-protein complex whose requirement is linked to the translational status of the cell. Mol Cell Biol 22(8):2564-74 SGD PMID 11909951
- ↑ Doma MK and Parker R (2006) Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation. Nature 440(7083):561-4 SGD PMID 16554824
- ↑ Nelson RJ, et al. (1992) The translation machinery and 70 kd heat shock protein cooperate in protein synthesis. Cell 71(1):97-105 SGD PMID 1394434
- ↑ Passos DO, et al. (2009) Analysis of Dom34 and its function in no-go decay. Mol Biol Cell 20(13):3025-32 SGD PMID 19420139
- ↑ Shoemaker CJ, et al. (2010) Dom34:Hbs1 promotes subunit dissociation and peptidyl-tRNA drop-off to initiate no-go decay. Science 330(6002):369-72 SGD PMID 20947765
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