Difference between revisions of "YKR063C"
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| − | '''Description of YKR063C:''' | + | '''Description of YKR063C:''' Protein required for pre-rRNA processing at both ends of ITS2; may coordinate the action of the Rat1p-Rai1p exoRNAse; required for the G1/S transition of the cell cycle; human ortholog is Las1L; mutants require the SSD1-v allele for viability<ref name='S000053118'>Doseff AI and Arndt KT (1995) LAS1 is an essential nuclear protein involved in cell morphogenesis and cell surface growth. Genetics 141(3):857-71 {{SGDpaper|S000053118}} PMID 8582632</ref><ref name='S000147449'>Schillewaert S, et al. (2011) The evolutionarily conserved protein LAS1 is required for pre-rRNA processing at both ends of ITS2. Mol Cell Biol () |
| − | {{SGDpaper| | + | {{SGDpaper|S000147449}} PMID 22083961</ref> |
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Revision as of 14:05, 29 November 2011
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| Systematic name | YKR063C |
| Gene name | LAS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:562297..560789 |
| Primary SGDID | S000001771 |
Description of YKR063C: Protein required for pre-rRNA processing at both ends of ITS2; may coordinate the action of the Rat1p-Rai1p exoRNAse; required for the G1/S transition of the cell cycle; human ortholog is Las1L; mutants require the SSD1-v allele for viability[1][2]
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References
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- ↑ Doseff AI and Arndt KT (1995) LAS1 is an essential nuclear protein involved in cell morphogenesis and cell surface growth. Genetics 141(3):857-71 SGD PMID 8582632
- ↑ Schillewaert S, et al. (2011) The evolutionarily conserved protein LAS1 is required for pre-rRNA processing at both ends of ITS2. Mol Cell Biol () SGD PMID 22083961
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