YKR063C

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Systematic name YKR063C
Gene name LAS1
Aliases
Feature type ORF, Verified
Coordinates Chr XI:562297..560789
Primary SGDID S000001771


Description of YKR063C: Protein required for pre-rRNA processing at both ends of ITS2; may coordinate the action of the Rat1p-Rai1p exoRNAse; required for the G1/S transition of the cell cycle; human ortholog is Las1L; mutants require the SSD1-v allele for viability[1][2]




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References

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  1. Doseff AI and Arndt KT (1995) LAS1 is an essential nuclear protein involved in cell morphogenesis and cell surface growth. Genetics 141(3):857-71 SGD PMID 8582632
  2. Schillewaert S, et al. (2011) The evolutionarily conserved protein LAS1 is required for pre-rRNA processing at both ends of ITS2. Mol Cell Biol () SGD PMID 22083961

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