Difference between revisions of "YKL134C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001617 YKL134C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001617 YKL134C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''OCT1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''OCT1 ''
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'''Description of YKL134C:''' Mitochondrial intermediate peptidase, cleaves N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis<ref name='S000051417'>Branda SS, et al. (1999) Mitochondrial intermediate peptidase and the yeast frataxin homolog together maintain mitochondrial iron homeostasis in Saccharomyces cerevisiae. Hum Mol Genet 8(6):1099-110 {{SGDpaper|S000051417}} PMID 10332043</ref><ref name='S000057577'>Isaya G, et al. (1994) MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae. Mol Cell Biol 14(8):5603-16
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'''Description of YKL134C:''' Mitochondrial intermediate peptidase, cleaves destabilizing N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis<ref name='S000051417'>Branda SS, et al. (1999) Mitochondrial intermediate peptidase and the yeast frataxin homolog together maintain mitochondrial iron homeostasis in Saccharomyces cerevisiae. Hum Mol Genet 8(6):1099-110 {{SGDpaper|S000051417}} PMID 10332043</ref><ref name='S000057577'>Isaya G, et al. (1994) MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae. Mol Cell Biol 14(8):5603-16 {{SGDpaper|S000057577}} PMID 8035833</ref><ref name='S000145233'>Vogtle FN, et al. (2011) Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization. Mol Biol Cell ()
  {{SGDpaper|S000057577}} PMID 8035833</ref>
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  {{SGDpaper|S000145233}} PMID 21525245</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YKL134C
Gene name OCT1
Aliases
Feature type ORF, Verified
Coordinates Chr XI:191442..189124
Primary SGDID S000001617


Description of YKL134C: Mitochondrial intermediate peptidase, cleaves destabilizing N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis[1][2][3]




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References

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  1. Branda SS, et al. (1999) Mitochondrial intermediate peptidase and the yeast frataxin homolog together maintain mitochondrial iron homeostasis in Saccharomyces cerevisiae. Hum Mol Genet 8(6):1099-110 SGD PMID 10332043
  2. Isaya G, et al. (1994) MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae. Mol Cell Biol 14(8):5603-16 SGD PMID 8035833
  3. Vogtle FN, et al. (2011) Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization. Mol Biol Cell () SGD PMID 21525245

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