YKL134C
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| Systematic name | YKL134C |
| Gene name | OCT1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:191442..189124 |
| Primary SGDID | S000001617 |
Description of YKL134C: Mitochondrial intermediate peptidase, cleaves destabilizing N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis[1][2][3]
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References
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- ↑ Branda SS, et al. (1999) Mitochondrial intermediate peptidase and the yeast frataxin homolog together maintain mitochondrial iron homeostasis in Saccharomyces cerevisiae. Hum Mol Genet 8(6):1099-110 SGD PMID 10332043
- ↑ Isaya G, et al. (1994) MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae. Mol Cell Biol 14(8):5603-16 SGD PMID 8035833
- ↑ Vogtle FN, et al. (2011) Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization. Mol Biol Cell () SGD PMID 21525245
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