Difference between revisions of "YJR099W"

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'''Description of YJR099W:''' Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p<ref name='S000041793'>Sakamoto T, et al. (1999) An NMR analysis of ubiquitin recognition by yeast ubiquitin hydrolase: evidence for novel substrate recognition by a cysteine protease. Biochemistry 38(36):11634-42 {{SGDpaper|S000041793}} PMID 10512618</ref><ref name='S000080739'>Larsen CN, et al. (1998) Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases. Biochemistry 37(10):3358-68 {{SGDpaper|S000080739}} PMID 9521656</ref><ref name='S000071659'>Linghu B, et al. (2002) Rub1p processing by Yuh1p is required for wild-type levels of Rub1p conjugation to Cdc53p. Eukaryot Cell 1(3):491-4
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'''Description of YJR099W:''' Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p<ref name='S000080739'>Larsen CN, et al. (1998) Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases. Biochemistry 37(10):3358-68 {{SGDpaper|S000080739}} PMID 9521656</ref><ref name='S000071659'>Linghu B, et al. (2002) Rub1p processing by Yuh1p is required for wild-type levels of Rub1p conjugation to Cdc53p. Eukaryot Cell 1(3):491-4 {{SGDpaper|S000071659}} PMID 12455997</ref><ref name='S000041793'>Sakamoto T, et al. (1999) An NMR analysis of ubiquitin recognition by yeast ubiquitin hydrolase: evidence for novel substrate recognition by a cysteine protease. Biochemistry 38(36):11634-42
  {{SGDpaper|S000071659}} PMID 12455997</ref>
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  {{SGDpaper|S000041793}} PMID 10512618</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YJR099W
Gene name YUH1
Aliases
Feature type ORF, Verified
Coordinates Chr X:615565..616275
Primary SGDID S000003860


Description of YJR099W: Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p[1][2][3]




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References

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  1. Larsen CN, et al. (1998) Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases. Biochemistry 37(10):3358-68 SGD PMID 9521656
  2. Linghu B, et al. (2002) Rub1p processing by Yuh1p is required for wild-type levels of Rub1p conjugation to Cdc53p. Eukaryot Cell 1(3):491-4 SGD PMID 12455997
  3. Sakamoto T, et al. (1999) An NMR analysis of ubiquitin recognition by yeast ubiquitin hydrolase: evidence for novel substrate recognition by a cysteine protease. Biochemistry 38(36):11634-42 SGD PMID 10512618

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