YJR099W
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| Systematic name | YJR099W |
| Gene name | YUH1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr X:615576..616286 |
| Primary SGDID | S000003860 |
Description of YJR099W: Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p[1][2][3]
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References
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- ↑ Larsen CN, et al. (1998) Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases. Biochemistry 37(10):3358-68 SGD PMID 9521656
- ↑ Linghu B, et al. (2002) Rub1p processing by Yuh1p is required for wild-type levels of Rub1p conjugation to Cdc53p. Eukaryot Cell 1(3):491-4 SGD PMID 12455997
- ↑ Sakamoto T, et al. (1999) An NMR analysis of ubiquitin recognition by yeast ubiquitin hydrolase: evidence for novel substrate recognition by a cysteine protease. Biochemistry 38(36):11634-42 SGD PMID 10512618
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