Difference between revisions of "YJR086W"
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| − | '''Description of YJR086W:''' G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling<ref name='S000045208'>Whiteway M, et al. (1989) The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein. Cell 56(3):467-77 {{SGDpaper|S000045208}} PMID 2536595 | + | '''Description of YJR086W:''' G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling<ref name='S000046851'>Hirschman JE and Jenness DD (1999) Dual lipid modification of the yeast ggamma subunit Ste18p determines membrane localization of Gbetagamma. Mol Cell Biol 19(11):7705-11 {{SGDpaper|S000046851}} PMID 10523659</ref><ref name='S000045208'>Whiteway M, et al. (1989) The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein. Cell 56(3):467-77 |
| − | + | {{SGDpaper|S000045208}} PMID 2536595</ref> | |
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Revision as of 14:05, 25 February 2010
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| Systematic name | YJR086W |
| Gene name | STE18 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr X:586060..586392 |
| Primary SGDID | S000003846 |
Description of YJR086W: G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling[1][2]
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Contents
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References
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- ↑ Hirschman JE and Jenness DD (1999) Dual lipid modification of the yeast ggamma subunit Ste18p determines membrane localization of Gbetagamma. Mol Cell Biol 19(11):7705-11 SGD PMID 10523659
- ↑ Whiteway M, et al. (1989) The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein. Cell 56(3):467-77 SGD PMID 2536595
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