YJR086W
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Systematic name | YJR086W |
Gene name | STE18 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr X:586068..586400 |
Primary SGDID | S000003846 |
Description of YJR086W: G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling[1][2]
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References
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- Jump up ↑ Hirschman JE and Jenness DD (1999) Dual lipid modification of the yeast ggamma subunit Ste18p determines membrane localization of Gbetagamma. Mol Cell Biol 19(11):7705-11 SGD PMID 10523659
- Jump up ↑ Whiteway M, et al. (1989) The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein. Cell 56(3):467-77 SGD PMID 2536595
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