YJR086W

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Systematic name YJR086W
Gene name STE18
Aliases
Feature type ORF, Verified
Coordinates Chr X:586068..586400
Primary SGDID S000003846


Description of YJR086W: G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling[1][2]




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References

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  1. Hirschman JE and Jenness DD (1999) Dual lipid modification of the yeast ggamma subunit Ste18p determines membrane localization of Gbetagamma. Mol Cell Biol 19(11):7705-11 SGD PMID 10523659
  2. Whiteway M, et al. (1989) The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein. Cell 56(3):467-77 SGD PMID 2536595

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