YJR057W

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Systematic name YJR057W
Gene name CDC8
Aliases
Feature type ORF, Verified
Coordinates Chr X:544055..544705
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Description of YJR057W: Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p[1][2]



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References

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  1. Jong AY and Campbell JL (1984) Characterization of Saccharomyces cerevisiae thymidylate kinase, the CDC8 gene product. General properties, kinetic analysis, and subcellular localization. J Biol Chem 259(23):14394-8 SGD PMID 6094555
  2. Abaigar LT, et al. (1992) Functional and structural conservation of Schizosaccharomyces pombe dTMP kinase gene. Biochim Biophys Acta 1132(2):222-4 SGD PMID 1327149

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