YJR057W

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Systematic name YJR057W
Gene name CDC8
Aliases
Feature type ORF, Verified
Coordinates Chr X:544062..544712
Primary SGDID S000003818


Description of YJR057W: Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p[1][2][3][4]




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References

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  1. Jump up Abaigar LT, et al. (1992) Functional and structural conservation of Schizosaccharomyces pombe dTMP kinase gene. Biochim Biophys Acta 1132(2):222-4 SGD PMID 1327149
  2. Jump up Jong AY and Campbell JL (1984) Characterization of Saccharomyces cerevisiae thymidylate kinase, the CDC8 gene product. General properties, kinetic analysis, and subcellular localization. J Biol Chem 259(23):14394-8 SGD PMID 6094555
  3. Jump up Jong AY, et al. (1984) The CDC8 gene of yeast encodes thymidylate kinase. J Biol Chem 259(17):11052-9 SGD PMID 6088527
  4. Jump up Sclafani RA and Fangman WL (1984) Yeast gene CDC8 encodes thymidylate kinase and is complemented by herpes thymidine kinase gene TK. Proc Natl Acad Sci U S A 81(18):5821-5 SGD PMID 6091111

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