YJR057W

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Systematic name YJR057W
Gene name CDC8
Aliases
Feature type ORF, Verified
Coordinates Chr X:544062..544712
Primary SGDID S000003818


Description of YJR057W: Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p[1][2][3][4]




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References

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  1. Abaigar LT, et al. (1992) Functional and structural conservation of Schizosaccharomyces pombe dTMP kinase gene. Biochim Biophys Acta 1132(2):222-4 SGD PMID 1327149
  2. Jong AY and Campbell JL (1984) Characterization of Saccharomyces cerevisiae thymidylate kinase, the CDC8 gene product. General properties, kinetic analysis, and subcellular localization. J Biol Chem 259(23):14394-8 SGD PMID 6094555
  3. Jong AY, et al. (1984) The CDC8 gene of yeast encodes thymidylate kinase. J Biol Chem 259(17):11052-9 SGD PMID 6088527
  4. Sclafani RA and Fangman WL (1984) Yeast gene CDC8 encodes thymidylate kinase and is complemented by herpes thymidine kinase gene TK. Proc Natl Acad Sci U S A 81(18):5821-5 SGD PMID 6091111

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