YGR163W

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Systematic name YGR163W
Gene name GTR2
Aliases
Feature type ORF, Verified
Coordinates Chr VII:827557..828582
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Description of YGR163W: Cytoplasmic GTP binding protein that negatively regulates Ran/Tc4 GTPase cycle; subunit of EGO complex, which is involved in microautophagy regulation, and of GSE complex, required for sorting of Gap1p; homolog of human RagC and RagD[1][2][3][4]



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References

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  1. Gao M and Kaiser CA (2006) A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast. Nat Cell Biol 8(7):657-67 SGD PMID 16732272
  2. Dubouloz F, et al. (2005) The TOR and EGO protein complexes orchestrate microautophagy in yeast. Mol Cell 19(1):15-26 SGD PMID 15989961
  3. Sekiguchi T, et al. (2001) Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B. J Biol Chem 276(10):7246-57 SGD PMID 11073942
  4. Nakashima N, et al. (1999) Saccharomyces cerevisiae putative G protein, Gtr1p, which forms complexes with itself and a novel protein designated as Gtr2p, negatively regulates the Ran/Gsp1p G protein cycle through Gtr2p. Genetics 152(3):853-67 SGD PMID 10388807

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