YGR163W
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| Systematic name | YGR163W |
| Gene name | GTR2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:827552..828577 |
| Primary SGDID | S000003395 |
Description of YGR163W: Putative GTP binding protein that negatively regulates Ran/Tc4 GTPase cycle; activates transcription; subunit of EGO and GSE complexes; required for sorting of Gap1p; localizes to cytoplasm and to chromatin; homolog of human RagC and RagD[1][2][3][4][5]
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References
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- ↑ Dubouloz F, et al. (2005) The TOR and EGO protein complexes orchestrate microautophagy in yeast. Mol Cell 19(1):15-26 SGD PMID 15989961
- ↑ Gao M and Kaiser CA (2006) A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast. Nat Cell Biol 8(7):657-67 SGD PMID 16732272
- ↑ Nakashima N, et al. (1999) Saccharomyces cerevisiae putative G protein, Gtr1p, which forms complexes with itself and a novel protein designated as Gtr2p, negatively regulates the Ran/Gsp1p G protein cycle through Gtr2p. Genetics 152(3):853-67 SGD PMID 10388807
- ↑ Sekiguchi T, et al. (2001) Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B. J Biol Chem 276(10):7246-57 SGD PMID 11073942
- ↑ Sekiguchi T, et al. (2008) Genetic evidence that Ras-like GTPases, Gtr1p, and Gtr2p, are involved in epigenetic control of gene expression in Saccharomyces cerevisiae. Biochem Biophys Res Commun 368(3):748-54 SGD PMID 18258182
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