Difference between revisions of "YFL031W"
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr VI:75177..76145 | |nowrap| Chr VI:75177..76145 | ||
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==Community Commentary== | ==Community Commentary== | ||
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==References== | ==References== | ||
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Revision as of 08:17, 30 January 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YFL031W |
| Gene name | HAC1 |
| Aliases | ERN4, IRE15 |
| Feature type | ORF, Verified |
| Coordinates | Chr VI:75177..76145 |
Description of YFL031W: bZIP transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway utilizing Ire1p, Trl1p and Ada5p facilitates efficient Hac1p synthesis[1][2][3][4][5][6][7][8][9][10]
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Contents
Community Commentary
About Community Commentary. Please share your knowledge!
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References
See Help:References on how to add references
- ↑ Mori K, et al. (1996) Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway. Genes Cells 1(9):803-17 SGD PMID 9077435
- ↑ Gonzalez TN, et al. (1999) Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway. EMBO J 18(11):3119-32 SGD PMID 10357823
- ↑ Chapman RE and Walter P (1997) Translational attenuation mediated by an mRNA intron. Curr Biol 7(11):850-9 SGD PMID 9382810
- ↑ Mori K, et al. (1998) Palindrome with spacer of one nucleotide is characteristic of the cis-acting unfolded protein response element in Saccharomyces cerevisiae. J Biol Chem 273(16):9912-20 SGD PMID 9545334
- ↑ Kaufman RJ (1999) Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev 13(10):1211-33 SGD PMID 10346810
- ↑ Sidrauski C and Walter P (1997) The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell 90(6):1031-9 SGD PMID 9323131
- ↑ Kawahara T, et al. (1997) Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response. Mol Biol Cell 8(10):1845-62 SGD PMID 9348528
- ↑ Cox JS and Walter P (1996) A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response. Cell 87(3):391-404 SGD PMID 8898193
- ↑ Nojima H, et al. (1994) Hac1: a novel yeast bZIP protein binding to the CRE motif is a multicopy suppressor for cdc10 mutant of Schizosaccharomyces pombe. Nucleic Acids Res 22(24):5279-88 SGD PMID 7816617
- ↑ Welihinda AA, et al. (2000) The transcriptional co-activator ADA5 is required for HAC1 mRNA processing in vivo. J Biol Chem 275(5):3377-81 SGD PMID 10652329
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