YEL060C

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Systematic name YEL060C
Gene name PRB1
Aliases CVT1
Feature type ORF, Verified
Coordinates Chr V:41953..40046
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Description of YEL060C: Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation[1][2][3]



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References

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  1. Teichert U, et al. (1989) Lysosomal (vacuolar) proteinases of yeast are essential catalysts for protein degradation, differentiation, and cell survival. J Biol Chem 264(27):16037-45 SGD PMID 2674123
  2. Zubenko GS and Jones EW (1981) Protein degradation, meiosis and sporulation in proteinase-deficient mutants of Saccharomyces cerevisiae. Genetics 97(1):45-64 SGD PMID 7021321
  3. Moehle CM, et al. (1987) Protease B of the lysosomelike vacuole of the yeast Saccharomyces cerevisiae is homologous to the subtilisin family of serine proteases. Mol Cell Biol 7(12):4390-9 SGD PMID 3325823

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