YEL060C
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| Systematic name | YEL060C |
| Gene name | PRB1 |
| Aliases | CVT1 |
| Feature type | ORF, Verified |
| Coordinates | Chr V:41953..40046 |
| Primary SGDID | S000000786 |
Description of YEL060C: Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation; activity inhibited by Pbi2p[1][2][3][4]
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References
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- ↑ Moehle CM, et al. (1987) Protease B of the lysosomelike vacuole of the yeast Saccharomyces cerevisiae is homologous to the subtilisin family of serine proteases. Mol Cell Biol 7(12):4390-9 SGD PMID 3325823
- ↑ Schu P, et al. (1991) The proteinase yscB inhibitor (PB12) gene of yeast and studies on the function of its protein product. Eur J Biochem 197(1):1-7 SGD PMID 2015812
- ↑ Teichert U, et al. (1989) Lysosomal (vacuolar) proteinases of yeast are essential catalysts for protein degradation, differentiation, and cell survival. J Biol Chem 264(27):16037-45 SGD PMID 2674123
- ↑ Zubenko GS and Jones EW (1981) Protein degradation, meiosis and sporulation in proteinase-deficient mutants of Saccharomyces cerevisiae. Genetics 97(1):45-64 SGD PMID 7021321
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