Difference between revisions of "YEL013W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000739 YEL013W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VAC8 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VAC8 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr V:128825..130561 | |nowrap| Chr V:128825..130561 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000739 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YEL013W:''' Phosphorylated vacuolar membrane protein that interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions<ref name='S000056230'>Wang YX, et al. (1998) Vac8p, a vacuolar protein with armadillo repeats, functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole. J Cell Biol 140(5):1063-74 {{SGDpaper|S000056230}} PMID 9490720</ref><ref name='S000054987'>Scott SV, et al. (2000) Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting. J Biol Chem 275(33):25840-9 {{SGDpaper|S000054987}} PMID 10837477</ref><ref name='S000039257'>Pan X, et al. (2000) Nucleus-vacuole junctions in Saccharomyces cerevisiae are formed through the direct interaction of Vac8p with Nvj1p. Mol Biol Cell 11(7):2445-57 |
{{SGDpaper|S000039257}} PMID 10888680</ref> | {{SGDpaper|S000039257}} PMID 10888680</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:45, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YEL013W |
| Gene name | VAC8 |
| Aliases | YEB3 |
| Feature type | ORF, Verified |
| Coordinates | Chr V:128825..130561 |
| Primary SGDID | S000000739 |
Description of YEL013W: Phosphorylated vacuolar membrane protein that interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions[1][2][3]
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Community Commentary
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Interactions
Physical
Physical interaction with VAC17
Immunoprecipitating Vac17p with sheep anti-Vac17p antibody coprecipitates Vac8p. [4] [5]
Two Hybrid
Two Hybrid interaction with VAC17
Residues 290-380 of Vac17p interact with Vac8p in a yeast two-hybrid analysis. [4] [5]
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References
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- ↑ Wang YX, et al. (1998) Vac8p, a vacuolar protein with armadillo repeats, functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole. J Cell Biol 140(5):1063-74 SGD PMID 9490720
- ↑ Scott SV, et al. (2000) Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting. J Biol Chem 275(33):25840-9 SGD PMID 10837477
- ↑ Pan X, et al. (2000) Nucleus-vacuole junctions in Saccharomyces cerevisiae are formed through the direct interaction of Vac8p with Nvj1p. Mol Biol Cell 11(7):2445-57 SGD PMID 10888680
- ↑ 4.0 4.1 Tang F, et al. (2003) Regulated degradation of a class V myosin receptor directs movement of the yeast vacuole. Nature 422(6927):87-92 SGD PMID 12594460
- ↑ 5.0 5.1 submitted by Fusheng Tang on 2003-03-17
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