Difference between revisions of "YDR372C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002780 YDR372C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VPS74 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''VPS74 '' | ||
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''API1'' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''API1, MNN3'' |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:1222149..1221112 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002780 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002780 | ||
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| − | '''Description of YDR372C:''' | + | '''Description of YDR372C:''' Protein required for Golgi localization of glycosyltransferases; binds the cytosolic domains of Golgi glycosyltransferases; binding to PtdIns4P required for Golgi targeting and function; tetramer formation required for function<ref name='S000126120'>Schmitz KR, et al. (2008) Golgi localization of glycosyltransferases requires a Vps74p oligomer. Dev Cell 14(4):523-34 {{SGDpaper|S000126120}} PMID 18410729</ref><ref name='S000132652'>Wood CS, et al. (2009) PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking. J Cell Biol 187(7):967-75 |
| − | {{SGDpaper| | + | {{SGDpaper|S000132652}} PMID 20026658</ref> |
<br> | <br> | ||
<br> | <br> | ||
Latest revision as of 07:45, 23 January 2012
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| Systematic name | YDR372C |
| Gene name | VPS74 |
| Aliases | API1, MNN3 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1222149..1221112 |
| Primary SGDID | S000002780 |
Description of YDR372C: Protein required for Golgi localization of glycosyltransferases; binds the cytosolic domains of Golgi glycosyltransferases; binding to PtdIns4P required for Golgi targeting and function; tetramer formation required for function[1][2]
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References
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- ↑ Schmitz KR, et al. (2008) Golgi localization of glycosyltransferases requires a Vps74p oligomer. Dev Cell 14(4):523-34 SGD PMID 18410729
- ↑ Wood CS, et al. (2009) PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking. J Cell Biol 187(7):967-75 SGD PMID 20026658
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