YDR372C
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| Systematic name | YDR372C |
| Gene name | VPS74 |
| Aliases | API1, MNN3 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1222149..1221112 |
| Primary SGDID | S000002780 |
Description of YDR372C: Protein required for Golgi localization of glycosyltransferases; binds the cytosolic domains of Golgi glycosyltransferases; binding to PtdIns4P required for Golgi targeting and function; tetramer formation required for function[1][2]
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References
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- ↑ Schmitz KR, et al. (2008) Golgi localization of glycosyltransferases requires a Vps74p oligomer. Dev Cell 14(4):523-34 SGD PMID 18410729
- ↑ Wood CS, et al. (2009) PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking. J Cell Biol 187(7):967-75 SGD PMID 20026658
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