Difference between revisions of "YDR372C"

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'''Description of YDR372C:''' Non-essential protein of unknown function involved in vacuolar protein sorting; belongs to a family of cytosolic Golgi-associated proteins suggesting that it may play a role in secretion; also detected in the nucleus<ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000070264'>Bonangelino CJ, et al. (2002) Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Mol Biol Cell 13(7):2486-501
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'''Description of YDR372C:''' Protein required for Golgi localization of glycosyltransferases; binds the cytosolic domains of Golgi glycosyltransferases; functions as a heterotetramer<ref name='S000126120'>Schmitz KR, et al. (2008) Golgi localization of glycosyltransferases requires a Vps74p oligomer. Dev Cell 14(4):523-34
  {{SGDpaper|S000070264}} PMID 12134085</ref>
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  {{SGDpaper|S000126120}} PMID 18410729</ref>
 
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Revision as of 14:05, 22 April 2008

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Systematic name YDR372C
Gene name VPS74
Aliases API1
Feature type ORF, Verified
Coordinates Chr IV:1222141..1221104
Primary SGDID S000002780


Description of YDR372C: Protein required for Golgi localization of glycosyltransferases; binds the cytosolic domains of Golgi glycosyltransferases; functions as a heterotetramer[1]




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References

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  1. Schmitz KR, et al. (2008) Golgi localization of glycosyltransferases requires a Vps74p oligomer. Dev Cell 14(4):523-34 SGD PMID 18410729

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