Difference between revisions of "YDR139C"

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'''Description of YDR139C:''' Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)<ref name='S000075344'>Laplaza JM, et al. (2004) Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo. Biochem J 377(Pt 2):459-67 {{SGDpaper|S000075344}} PMID 14519104</ref><ref name='S000061637'>Hochstrasser M (2000) Biochemistry. All in the ubiquitin family. Science 289(5479):563-4 {{SGDpaper|S000061637}} PMID 10939967</ref><ref name='S000050724'>Liakopoulos D, et al. (1998) A novel protein modification pathway related to the ubiquitin system. EMBO J 17(8):2208-14 {{SGDpaper|S000050724}} PMID 9545234</ref><ref name='S000042395'>Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26
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'''Description of YDR139C:''' Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)<ref name='S000042395'>Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26 {{SGDpaper|S000042395}} PMID 9531531</ref><ref name='S000050724'>Liakopoulos D, et al. (1998) A novel protein modification pathway related to the ubiquitin system. EMBO J 17(8):2208-14 {{SGDpaper|S000050724}} PMID 9545234</ref><ref name='S000061637'>Hochstrasser M (2000) Biochemistry. All in the ubiquitin family. Science 289(5479):563-4 {{SGDpaper|S000061637}} PMID 10939967</ref><ref name='S000075344'>Laplaza JM, et al. (2004) Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo. Biochem J 377(Pt 2):459-67
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  {{SGDpaper|S000075344}} PMID 14519104</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YDR139C
Gene name RUB1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:733922..733616
Primary SGDID S000002546


Description of YDR139C: Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)[1][2][3][4]




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References

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  1. Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26 SGD PMID 9531531
  2. Liakopoulos D, et al. (1998) A novel protein modification pathway related to the ubiquitin system. EMBO J 17(8):2208-14 SGD PMID 9545234
  3. Hochstrasser M (2000) Biochemistry. All in the ubiquitin family. Science 289(5479):563-4 SGD PMID 10939967
  4. Laplaza JM, et al. (2004) Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo. Biochem J 377(Pt 2):459-67 SGD PMID 14519104

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