Difference between revisions of "YDL028C"

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'''Description of YDL028C:''' Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p<ref name='S000069129'>Castillo AR, et al. (2002) The yeast protein kinase Mps1p is required for assembly of the integral spindle pole body component Spc42p. J Cell Biol 156(3):453-65 {{SGDpaper|S000069129}} PMID 11827982</ref><ref name='S000060774'>Friedman DB, et al. (2001) Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain. J Biol Chem 276(21):17958-67 {{SGDpaper|S000060774}} PMID 11278681</ref><ref name='S000047902'>Hardwick KG, et al. (1996) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273(5277):953-6 {{SGDpaper|S000047902}} PMID 8688079</ref><ref name='S000047704'>Luca FC and Winey M (1998) MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy. Mol Biol Cell 9(1):29-46 {{SGDpaper|S000047704}} PMID 9436989</ref><ref name='S000044607'>Lauze E, et al. (1995) Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase. EMBO J 14(8):1655-63
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'''Description of YDL028C:''' Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p<ref name='S000044607'>Lauze E, et al. (1995) Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase. EMBO J 14(8):1655-63 {{SGDpaper|S000044607}} PMID 7737118</ref><ref name='S000047704'>Luca FC and Winey M (1998) MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy. Mol Biol Cell 9(1):29-46 {{SGDpaper|S000047704}} PMID 9436989</ref><ref name='S000047902'>Hardwick KG, et al. (1996) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273(5277):953-6 {{SGDpaper|S000047902}} PMID 8688079</ref><ref name='S000060774'>Friedman DB, et al. (2001) Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain. J Biol Chem 276(21):17958-67 {{SGDpaper|S000060774}} PMID 11278681</ref><ref name='S000069129'>Castillo AR, et al. (2002) The yeast protein kinase Mps1p is required for assembly of the integral spindle pole body component Spc42p. J Cell Biol 156(3):453-65
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  {{SGDpaper|S000069129}} PMID 11827982</ref>
 
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Revision as of 04:15, 19 December 2008

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Systematic name YDL028C
Gene name MPS1
Aliases RPK1
Feature type ORF, Verified
Coordinates Chr IV:403289..400995
Primary SGDID S000002186


Description of YDL028C: Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p[1][2][3][4][5]




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References

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  1. Lauze E, et al. (1995) Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase. EMBO J 14(8):1655-63 SGD PMID 7737118
  2. Luca FC and Winey M (1998) MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy. Mol Biol Cell 9(1):29-46 SGD PMID 9436989
  3. Hardwick KG, et al. (1996) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273(5277):953-6 SGD PMID 8688079
  4. Friedman DB, et al. (2001) Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain. J Biol Chem 276(21):17958-67 SGD PMID 11278681
  5. Castillo AR, et al. (2002) The yeast protein kinase Mps1p is required for assembly of the integral spindle pole body component Spc42p. J Cell Biol 156(3):453-65 SGD PMID 11827982

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