YDL028C
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| Systematic name | YDL028C |
| Gene name | MPS1 |
| Aliases | RPK1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:403291..400997 |
| Primary SGDID | S000002186 |
Description of YDL028C: Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p[1][2][3][4][5]
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References
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- ↑ Castillo AR, et al. (2002) The yeast protein kinase Mps1p is required for assembly of the integral spindle pole body component Spc42p. J Cell Biol 156(3):453-65 SGD PMID 11827982
- ↑ Friedman DB, et al. (2001) Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain. J Biol Chem 276(21):17958-67 SGD PMID 11278681
- ↑ Hardwick KG, et al. (1996) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273(5277):953-6 SGD PMID 8688079
- ↑ Lauze E, et al. (1995) Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase. EMBO J 14(8):1655-63 SGD PMID 7737118
- ↑ Luca FC and Winey M (1998) MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy. Mol Biol Cell 9(1):29-46 SGD PMID 9436989
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