YML069W

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Systematic name YML069W
Gene name POB3
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:135500..137158
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Description of YML069W: Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure[1][2]



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References

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  1. Brewster NK, et al. (1998) Characterization of the CP complex, an abundant dimer of Cdc68 and Pob3 proteins that regulates yeast transcriptional activation and chromatin repression. J Biol Chem 273(34):21972-9 SGD PMID 9705338
  2. Evans DR, et al. (1998) The yeast protein complex containing cdc68 and pob3 mediates core-promoter repression through the cdc68 N-terminal domain. Genetics 150(4):1393-405 SGD PMID 9832518

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