YGR175C
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| Systematic name | YGR175C | |
| Gene name | ERG1 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr VII:848428..846938 | |
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Description of YGR175C: Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine[1][2]
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References
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- ↑ Satoh T, et al. (1993) Enzymatic properties of squalene epoxidase from Saccharomyces cerevisiae. Biol Pharm Bull 16(4):349-52 SGD PMID 8358382
- ↑ Jandrositz A, et al. (1991) The gene encoding squalene epoxidase from Saccharomyces cerevisiae: cloning and characterization. Gene 107(1):155-60 SGD PMID 1743514
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