YGR098C
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| Systematic name | YGR098C | |
| Gene name | ESP1 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr VII:687462..682570 | |
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Description of YGR098C: Separase with cysteine protease activity (related to caspases) that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibited by Pds1p[1][2]
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References
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- ↑ Uhlmann F, et al. (2000) Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast. Cell 103(3):375-86 SGD PMID 11081625
- ↑ Ciosk R, et al. (1998) An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell 93(6):1067-76 SGD PMID 9635435
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