YJR040W

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Systematic name YJR040W
Gene name GEF1
Aliases CLC
Feature type ORF, Verified
Coordinates Chr X:507739..510078


Description of YJR040W: Chloride channel localized to late- or post-Golgi vesicles, involved in iron metabolism; highly homologous to voltage-gated chloride channels in vertebrates[1][2]




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References

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  1. Flis K, et al. (2002) The Gef1 protein of Saccharomyces cerevisiae is associated with chloride channel activity. Biochem Biophys Res Commun 294(5):1144-50 SGD PMID 12074596
  2. Gaxiola RA, et al. (1998) The yeast CLC chloride channel functions in cation homeostasis. Proc Natl Acad Sci U S A 95(7):4046-50 SGD PMID 9520490

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