YJR040W

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Systematic name YJR040W
Gene name GEF1
Aliases CLC
Feature type ORF, Verified
Coordinates Chr X:507746..510085
Primary SGDID S000003801


Description of YJR040W: Voltage-gated chloride channel localized to the golgi, the endosomal system, and plasma membrane, and involved in cation homeostasis; highly homologous to vertebrate voltage-gated chloride channels[1][2][3]




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References

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  1. Flis K, et al. (2002) The Gef1 protein of Saccharomyces cerevisiae is associated with chloride channel activity. Biochem Biophys Res Commun 294(5):1144-50 SGD PMID 12074596
  2. Gaxiola RA, et al. (1998) The yeast CLC chloride channel functions in cation homeostasis. Proc Natl Acad Sci U S A 95(7):4046-50 SGD PMID 9520490
  3. Lopez-Rodriguez A, et al. (2007) The product of the gene GEF1 of Saccharomyces cerevisiae transports Cl across the plasma membrane. FEMS Yeast Res 7(8):1218-29 SGD PMID 17662057

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