YPL249C

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Systematic name YPL249C
Gene name GYP5
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:79353..76669


Description of YPL249C: GTPase-activating protein (GAP) for yeast Rab family members, involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p[1][2][3]




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References

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  1. Friesen H, et al. (2005) Interaction of the Saccharomyces cerevisiae cortical actin patch protein Rvs167p with proteins involved in ER to Golgi vesicle trafficking. Genetics 170(2):555-68 SGD PMID 15802519
  2. De Antoni A, et al. (2002) Significance of GTP hydrolysis in Ypt1p-regulated endoplasmic reticulum to Golgi transport revealed by the analysis of two novel Ypt1-GAPs. J Biol Chem 277(43):41023-31 SGD PMID 12189143
  3. Bon E, et al. (2000) A network of proteins around Rvs167p and Rvs161p, two proteins related to the yeast actin cytoskeleton. Yeast 16(13):1229-41 SGD PMID 10992286

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