YPL249C
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| Systematic name | YPL249C |
| Gene name | GYP5 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:79353..76669 |
| Primary SGDID | S000006170 |
Description of YPL249C: GTPase-activating protein (GAP) for yeast Rab family members; involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth[1][2][3][4]
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References
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- Jump up ↑ Bon E, et al. (2000) A network of proteins around Rvs167p and Rvs161p, two proteins related to the yeast actin cytoskeleton. Yeast 16(13):1229-41 SGD PMID 10992286
- Jump up ↑ De Antoni A, et al. (2002) Significance of GTP hydrolysis in Ypt1p-regulated endoplasmic reticulum to Golgi transport revealed by the analysis of two novel Ypt1-GAPs. J Biol Chem 277(43):41023-31 SGD PMID 12189143
- Jump up ↑ Friesen H, et al. (2005) Interaction of the Saccharomyces cerevisiae cortical actin patch protein Rvs167p with proteins involved in ER to Golgi vesicle trafficking. Genetics 170(2):555-68 SGD PMID 15802519
- Jump up ↑ Prigent M, et al. (2011) The RabGAP proteins Gyp5p and Gyl1p recruit the BAR domain protein Rvs167p for polarized exocytosis.LID - 10.1111/j.1600-0854.2011.01218.x [doi] Traffic () SGD PMID 21554509
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